That red, swollen, painful feeling at the site of an injury or infection can be unpleasant – but it is also a fundamental part of the body’s mechanism for healing. It’s called inflammation.
The body’s quick and effective regulation of inflammatory responses is necessary for optimal health and survival.
Unfortunately, the mechanism of inflammation can become impaired, and may be triggered even in the absence of pathogenic threat or the need for tissue repair. This is when inflammation becomes chronic and can lead to a number of degenerative diseases including atherosclerosis and rheumatoid arthritis.
Thankfully, improving the diet by avoiding foods that promote inflammation and increasing consumption of natural anti-inflammatory foods can reverse such chronic conditions.
Today’s article will discuss: (click to read)
- What inflammation is, including its causes
- The top 7 natural anti-inflammatory foods to help bring back balance and fight against chronic inflammation
Inflammation is the complex cascade of events involving recruitment of the immune system to help fight against injury and infection. It is characterized by a few key physical signs including pain, heat, swelling, and redness. These symptoms are what mobilize the immune system for action by recruiting white blood cells to the site of damage and initiating tissue repair and healing through rapid cellular division.
These events are regulated by the signalling pathways of various proteins, including pro-inflammatory cytokines. Once any threat of infection is removed and the tissue begins to heal, the inflammatory response is counteracted by anti-inflammatory pathways, returning the body to a state of balance and stability.
Depending on the severity of the threat to the tissue, an acute inflammatory response can last from a few hours to days or weeks. However, the state of inflammation eventually subsides once the injury from trauma has been resolved.
Failure to properly regulate inflammatory responses is the basis of chronic inflammation. This chronic condition is characterized by overproduction of proteins and related chemicals involved in inflammatory responses, as well as the infiltration of inflammatory cells in areas where they are not normally found.
These factors are destructive over a prolonged period of time, and contribute to the development of chronic diseases of inflammation. Such diseases include rheumatoid arthritis, atherosclerosis, Crohn’s disease, ulcerative colitis, respiratory distress syndrome and cancer.
This lack of inflammatory control by the body is in large part due to the pro-inflammatory foods that are prevalent in today’s society. These include diets high in refined starches, sugar, and trans fats, and low in antioxidants, fruits, vegetables, and omega-3 fatty acids.
The following list of natural anti-inflammatory foods provide the body with the needed nutrients and antioxidants to eliminate the chronic state of inflammation.
#1. Wild, Oily Fish
Fish such as salmon, trout, mackerel, sardines, and herring all have something in common, which is oil in their tissues that is rich in omega-3 fatty acids. Studies have shown that omega-3s are beneficial for rheumatoid arthritis, inflammatory bowel disease, and asthma.
A study comparing ibuprofen (e.g., Advil) and fish oil supplementation found that fish oil had an equivalent effect in reducing arthritic pain. Many of the patients of the study also discontinued their prescription medication in favor of continued fish oil supplementation.
The anti-inflammatory properties of omega-3 fatty acids is further demonstrated by their ability to decrease blood levels of cytokines that promote inflammation.
Turmeric is a yellow-orange spice commonly used in curries and Indian cuisine. Its anti-inflammatory properties have been known for thousands of years, where it was commonly used as a remedy for many ailments in ancient traditions. The potency of this spice is thanks to curcumin, a yellow pigment that is a major component of turmeric.
Research on turmeric in the past two decades has revealed its anti-inflammatory activity is due to the regulation of numerous enzymes, cytokines and other proteins involved in inflammation.
The polyphenols in berries are the most notable compounds that give them their anti-inflammatory activity. One study showed the potency of blueberry extract to inhibit the activity of inflammation-related enzymes. Another study showed how raspberry extract contributed to inhibition of inflammation and cartilage damage associated with arthritis.
#4. Cruciferous Vegetables
Vegetables such as cauliflower, cabbage, bok choy, and broccoli belong to the Cruciferous family and share inflammation-lowering properties. Specifically, the bioactive components of these vegetables are two compounds called I3C (indole-3-carbinol) and PEITC (beta-phenylethyl isothiocyanate). Their anti-inflammatory characteristics come from their ability to inhibit the levels of various cytokines involved in inflammation response.
This amazing root acts by modulating the relevant biochemical pathways involved in chronic inflammation. One such example is the ability of ginger to reduce the levels of prostaglandins in the blood. Prostaglandins are hormone-like compounds involved in cell signaling, with a diverse set of functions in the body – one of which involves the regulation of inflammation.
Ginger is a good addition to any diet, and can be added to stir-frys, stews, smoothies, and even made into a soothing and warming tea.
#7. Extra Virgin Olive Oil
The numerous phenolic compounds (i.e., polyphenols) are what give this oil its anti-inflammatory characteristics. Additionally, polyphenols are associated with antioxidant, anti-aging, and neuroprotective properties. Olive oil is a great addition to salad dressings and other food preparation that do not involve high heat.
The Bottom Line
There is a large array of foods with incredible anti-inflammatory properties. Their regular consumption to ameliorate conditions of chronic inflammation and overall health maintenance is highly encouraged. Because these foods have a diverse set of flavours – from the sweetness of berries, to crunchy vegetables and spices – they can be added to a variety of dishes and everyday meals.
What’s your favourite way to incorporate anti-inflammatory foods into your diet? Let me know in the comments!
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Berridge, M.J. (2012) Cell Stress, Inflammatory Responses and Cell Death. Cell Signalling Biology. 11:1-29.
Calder, P.C., Albers, R., Antoine, J.M., Blum, S., Bourdet-Sicard, R., et al. (2009) Inflammatory disease processes and interactions with nutrition. Br J Nutr. 101 Suppl 1:S1-45.
Maroon, J.C., Bost, J.W., & Maroon, A. (2010) Natural anti-inflammatory agents for pain relief. Surg Neurol Int. 1: 80.
Coussens, L.M. & Werb, Z. (2002) Inflammation and cancer. Nature. 420(6917):860-7.
Galland L. Diet and inflammation. Nutr Clin Pract. 25(6):634-640.
Giugliano, D., Ceriello, A., & Esposito, K. (2006) The Effects of Diet on Inflammation: Emphasis on the Metabolic Syndrome. Journal of the American College of Cardiology. 48(4):677-685.
Calder, P.C. (2013) Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology? Br J Clin Pharmacol. 75(3):645-62.
Maroon, J.C. & Bost, J.W. (2006) Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain. Surg Neurol. 65(4):326-31.
Menon, V.P. & Sudheer, A.R. (2007) Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol. 595:105-125.
Aggarwal, B.B. & Harikumar, K.B. (2009) Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol. 41(1):40-59.
Joseph, S.V., Edirisinghe, I., & Burton-Freeman, B.M. (2014) Berries: Anti-inflammatory Effects in Humans. J Agric Food Chem. [Epub ahead of print]
Torri, E., Lemos, M., Caliari, V., Kassuya, C.A., Bastos, J.K., Andrade, S.F. (2007) Anti-inflammatory and antinociceptive properties of blueberry extract (Vaccinium corymbosum). J Pharm Pharmacol. 59(4):591-596.
Jean-Gilles, D., Li, L., Ma, H., Yuan, T., Chichester, C.O. 3rd, Seeram, N.P. (2012) Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model. J Agric Food Chem. 60(23):5755-5762.
Tsai, J.T., Liu, H.C., Chen, Y.H. (2010) Suppression of inflammatory mediators by cruciferous vegetable-derived indole-3-carbinol and phenylethyl isothiocyanate in lipopolysaccharide-activated macrophages. Mediators Inflamm. 2010:293642.
Grzanna, R., Lindmark, L., & Frondoza, C.G. (2005) Ginger–an herbal medicinal product with broad anti-inflammatory actions. J Med Food. 8(2):125-132.
Mashhadi, N.S., Ghiasvand, R., Askari, G., Hariri, M., Darvishi, L., Mofid, M.R. (2013) Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidence. Int J Prev Med. 4(Suppl 1):S36-42.
Jeena, K., Liju, V.B., Kuttan, R. Antioxidant, anti-inflammatory and antinociceptive activities of essential oil from ginger. Indian J Physiol Pharmacol. 57(1):51-62.
Thomson, M., Al-Qattan, K.K., Al-Sawan, S.M., Alnaqeeb, M.A., Khan, I., Ali, M. (2002) The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. Prostaglandins Leukot Essent Fatty Acids. 67(6):475-8.
Lee da, Y., Li, H., Lim, H.J., Lee, H.J., Jeon, R., Ryu, J.H. (2012) Anti-inflammatory activity of sulfur-containing compounds from garlic. J Med Food. 15(11):992-9.
Sohn, D.W., Han, C.H., Jung, Y.S., Kim, S.I., Kim, S.W., Cho, Y.H. (2009) Anti-inflammatory and antimicrobial effects of garlic and synergistic effect between garlic and ciprofloxacin in a chronic bacterial prostatitis rat model. Int J Antimicrob Agents. 34(3):215-9.
Hodge, G., Hodge, S., Han, P. (2002) Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: potential therapeutic use in the treatment of inflammatory bowel disease. Cytometry. 48(4):209-15.
Lucas, L., Russell, A., Keast, R. (2011) Molecular mechanisms of inflammation. Anti-inflammatory benefits of virgin olive oil and the phenolic compound oleocanthal. Curr Pharm Des. 17(8):754-68.
Cárdeno, A., Sánchez-Hidalgo, M., Alarcón-de-la-Lastra, C. (2013) An up-date of olive oil phenols in inflammation and cancer: molecular mechanisms and clinical implications. Curr Med Chem. 20(37):4758-76.